The war has spread to Lebanon after Iran-backed Hezbollah fired rockets into northern Israel, with heavy bombing in Beirut.
Hopes of a rapid end to the war are receding as the rhetoric and violence escalate on both sides.
The US president and his Secretary of War said their military operation was ahead of schedule.
And whilst neither gave a timeframe for its end, getting rid of Ayatollah Khamenei has come at a price for America and its allies, from downed jets and spiralling commodities prices to the deaths of civilians and soldiers.
All the while, the truly achievable aims of the American and Israeli attacks remain unclear.