Ahmet Davutoglu said he would work with the US to establish a "safe area" for people displaced by Syria's conflict.
Mr Davutoglu did not rule out sending Turkish troops in to protect the area.
Turkey is home to more Syrian refugees than any other country - more than 1.8 million according to recent UN figures.
In a wide-ranging interview with the BBC's Jeremy Bowen, Mr Davutoglu called on the international community to do more to resolve the four-year conflict in Syria and denied that Turkey had helped so-called Islamic State and other extremist groups.
He criticised the five permanent members of the UN Security Council for failing to make a "strong decision" to stop the atrocities in Syria. (+ BBC video) » | Tuesday, August 11, 2015
