The teenager appears to have been bitten by an infected flea.
The authorities have sought to calm fears of an epidemic and have quarantined more than 100 people.
Bubonic plague, known as the Black Death when it killed an estimated 25 million people in Europe during the Middle Ages, is now rare.
The teenager, named as Temir Issakunov, came from a mountain village in the north-east of the country, close to the border with Kazakhstan.
"We suspect that the patient was infected with the plague through the bite of a flea," health ministry official Tolo Isakov said.
He said teams had been sent to the area to get rid of rodents, which host the fleas that can carry the deadly bacterium. » | Monday, August 26, 2013